XTANDI is a prescription medicine used for the treatment of prostate cancer in men that no longer responds to a medical or surgical treatment that lowers testosterone.
The most common side effects of Xtandi (Enzalutamide) include:
• Weakness or feeling more tired than usual
• Decreased appetite
• Hot flashes
• Joint pain
• A feeling that you or things around you are moving or spinning (vertigo)
• High blood pressure
• Weight loss
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A nonsteroidal antiandrogen (NSAA) prescription is used for the prevention of prostate cancer, Enzalutamide marketed under the Xtandi brand name. The therapy for metastatic castration resistant prostate cancer (mCRPC) and non-metastatic castration-resistant prostate cancer (MCSPC) and for metastatic castration-sensitive prostate cancer (mCSPC) is prescribed in combination with castration.
In the treatment of mCRPC, enzalutamide is clinically successful. After a month of opioid use there have been studies of a reduction of up to 89% of serum prostate specific antigen (PSA). Out of 65 patients with chemo naive and 38 out of 75 patients who underwent chemotherapy, the amount of PSA decreased more than 50 percent. For chemo-naive patients, the median progressions period was 56 weeks and for post-chemotherapy patients it was 25 weeks.
In the treatment of transgender women, enzalutamide may be used as an antiandrogen.