Fludara (Fludarabine)


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Fludara (Fludarabine) is an effective anti-cancer chemotherapy drug. It is considered as an antimetabolite. This drug helps in the treatment of chronic lymphocytic leukaemia (CLL), including CLL that has not responded to or reoccurred after standard therapy.


While being on this medication, one may experience the following side effects:

• Chills
• Fatigue
• Pain
• Sweating
• Numbness and tingling of hands and feet
• Shortness of breath (see lung problems)
• Diarrhoea
• Rash (see skin reactions
• Swelling
• Taste changes, metallic taste


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FLUDEARA OR Infusion has fludara (fludarabine) bone phosphate, a vidarabine analog fluorinated nucleotide, a moderately defamation-resistant 9-p-D arabinofuranosiladenin (ara-A). Every sterile, solid cake lyophilized vial contains 50 mg of bone phosphate (fludarabine), 50 mg mannitol and sodiums, to change pH to 7,7 .


For adult patients who have not reacted to or who have not developed disease during the course of therapy with at least one normal alkylating-containing agent FLUDARA (fludarabine) FOR INJECTIÓN is recommended for the treatment. In previously untreated or non-refractory CLL patients, protection and efficacy of FLUDARA (fludarabine) For INJECTION have not been identified.


The prescribed dosage of FLUDARA adult (fludarabine) FOR INJECTION is 25 mg / m2 intravenously administered over a five consecutive days period of around 30 minutes per day. Treatment should begin every 5 days every 28 days. Based on evidence of hematologic or non hematological toxicity, the dosage should be reduced or deferred. If neurotoxicity happens, physicians should consider postponing or discontinuing a medication.

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